In 2001, the U.S. Department of Health and Human Services HHS) released its 25th report on the health of the nation titled Health, United States, 2001: With Urban and Rural Health Chartbook. The chartbook, compiled by the National Center for Health Statistics (NCHS) at the Centers for Disease Control and Prevention (CDC), illustrated trends and highlighted various priorities in urban and rural health. The Rural Health Reform Policy Research Center (RHRPRC) replicated the analyses conducted in 2001 using the most recent data available (2006-2011). This brief highlights key findings around heart disease.